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Seattle and San Francisco and presented at a July conference, saw about a two-thirds overall reduction in STDs among gay and bi men and trans women. A previous French study, published in 2017, found the Official Human Souls For The Satanist Shirt Furthermore, I will do this intervention dramatically cut syphilis and chlamydia infections, but did not affect gonorrhea. “The data show in men a consistent benefit in terms of reducing the incidence of bacterial STIs,” Dr. Jean-Michel Molina, the lead author of both of the French studies and an LGBTQ health researcher at the Université Paris Cité, told NBC News, referring to the term sexually transmitted infections. He added that more research is needed to confirm the efficacy of the vaccine for gonorrhea. Paul Marcelin, 48, a software engineer living in Alameda, California, participated in the Seattle-San Francisco study and was randomized into the control group that did not receive the antibiotic. After the study was discontinued early due to high efficacy, he was offered doxyPEP last summer. “It’s been very, very positive, having that as an extra source of peace of mind,” Marcelin said of his experience taking doxycycline for prevention, noting that he typically contracts an STD about once every two years and has had none since starting doxyPEP. “It’s just part of my health routine.” Gay and bi men, plus transgender women, have been the focus of most of the recent research into pharmacological prevention of STDs, because they have a higher rate of such infections than cisgender heterosexual people (lesbians, meanwhile, have lower rates than heterosexual people). Men who have sex with men, for example, comprise less than 2% of the U.S. adult population but, according to the CDC, account for more than 40% of U.S. syphilis diagnoses. Over the past two decades, gonorrhea, chlamydia and syphilis have soared, to 2.5 million cases in 2021. The CDC estimates this has saddled the nation with $1.1 billion
in direct medical costs. Most critically, syphilis — a scourge that was nearly eliminated in late 1990s but that the Official Human Souls For The Satanist Shirt Furthermore, I will do this CDC reports skyrocketed by 68% between 2017 and 2021, to 171,000 cases — poses a potentially fatal threat to infants born to undiagnosed women. In rare cases, it can also harm vision or even cause blindness. David Harvey, executive director of the National Coalition of STD Directors, said the overall infection surge is driven, in part, by federal cuts to state STD programs. Condom use among gay and bisexual men in particular has also seen a long decline since HIV became treatable, and thus less frightening, in 1996, and with the advent a decade ago of the HIV prevention pill, known as PrEP. Harvey, like many other public health experts, is looking to doxycycline, which typically costs pennies per pill, as a potent tool that could help turn the STD tide. DoxyPEP concerns Some infectious disease experts, however, remain gravely concerned that doxyPEP adoption could fuel the emergence of drug-resistant pathogens, especially staph. “Overall, my biggest fear is they’re not thinking about global antimicrobial resistance,” Fabian Kong of the University of Melbourne said of doxyPEP’s champions. “They’re just thinking about the STI world.” The World Health Organization lists antimicrobial resistance as one of the top 10 global public health threats facing humanity. Approved in the 1960s, doxycycline is prescribed widely to treat acne and rosacea, to treat or prevent Lyme disease, and to prevent malaria among travelers and the military. Other tetracyclines, the antibiotic class to which doxycycline belongs, have long been used in livestock production — to the concern of many infectious disease experts, who worry this fuels drug-resistant infections that can affect humans. Recommended OUT HEALTH AND WELLNESS Mpox is highly fatal among people with advanced HIV, study finds OUT NEWS Pride flag set on fire outside NYC restaurant For doxyPEP, such concern is perhaps
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