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this little fiber which we put into their brains, and we can shine just a little tiny bit of blue light to activate these neurons,” said Jonathan Lovelace, a staff research associate in Augustine’s lab and co-author of the Official Donny Benet Infinite Desires Shirt moreover I will buy this study. Recommended HEALTH NEWS Newborn syphilis cases have reached ‘dire levels,’ CDC says HEALTH NEWS As overdose rates rise, FDA calls for new medications to help curb stimulant addiction Once the neurons are activated, “these mice will maybe walk around for five seconds, and then spontaneously fall over and become still,” Lovelace said. “After a few more seconds, they’ll get back up and start walking around.” The mice exhibited other classic signs of fainting in humans: Their blood pressure, breathing and heart rates went down, their pupils dilated and their eyes rolled back into their heads. “We were able to replicate this typical, iconic eye roll,” Augustine said. “That also very tightly correlated with the time when the fainting episode happened.” The researchers also noticed that activating the neurons constricted blood vessels and reduced blood flow from the heart to the brain — two more characteristic signs of fainting. But Augustine said there’s more to learn. His team still doesn’t know what activates the nerve pathway in real life, or whether the findings neatly translate to humans. “There would be much more nuance to human fainting,” he said. What causes fainting in humans? Prior to the new research, scientists

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understood that people faint when there’s not enough blood entering or exiting the Official Donny Benet Infinite Desires Shirt moreover I will buy this heart, cutting off blood flow to the brain. “You’re not going to get blood to the rest of your body, including your brain, and you’ll pass out,” said Dr. Shamai Grossman, an associate professor of emergency medicine at Harvard Medical School who wasn’t involved in the study. Most of the time, fainting isn’t worrisome unless someone passes out while driving or injures themselves during a fall, Grossman said. Roughly 40% of people have a fainting spell in their lifetime, often triggered by something minor. “When you’re standing for a long period of time or when you’re thirsty, blood kind of pools in your legs, or in pregnant women when the fetus exerts pressure on your chest, it prevents blood from flowing back into the heart,” Augustine said. “Same thing when you have beginners playing musical instruments. They exert a lot of pressure on the chest and you tend to have fainting episodes.” Other people faint from emotional responses to hearing bad news or even something funny — most likely because their body over-activates their parasympathetic nervous system to calm them down. While doctors currently don’t have ways to prevent spontaneous fainting spells, Augustine said targeting the neurons identified in his study could be one approach. For instance, doctors could remove or replace certain genes involved in the vagus nerve pathway. “In the future when things like gene therapy or targeted nerve stimulation become more pronounced in humans, you now have targets to potentially probe,” he said.

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